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The marriage of Albert Einstein and Mileva Marić _:e a bio:Marriage ; dc:date “1903” ; bio:partner < http:///resource/Albert_Einstein> ; bio:partner < http:///resource/Mileva_Mari%C4%87> ; bio:place < http:///resource/Bern> . Status
With the advent of next-generation sequencing we are obtaining enough sequence data to map the genes of complex diseases such as diabetes ,  infertility ,  breast cancer  or Alzheimer's Disease .  Genome-wide association studies are a useful approach to pinpoint the mutations responsible for such complex diseases.  Through these studies, thousands of DNA variants have been identified that are associated with similar diseases and traits.  Furthermore, the possibility for genes to be used at prognosis, diagnosis or treatment is one of the most essential applications. Many studies are discussing both the promising ways to choose the genes to be used and the problems and pitfalls of using genes to predict disease presence or prognosis.